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In rats, however, doses as low as 1 3 the oral mrdhd 1 15 the mrdhd on a mg m basis of clonidine were associated with increased resorptions in a study in which dams were treated continuously from 2 months prior to mating.

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Possible additive bradycardia, av block when clonidine is used with drugs that affect sinus nodal function or av nodal conduction 101 114.

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