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Viramune can cause serious liver damage and skin reactions that can cause death.

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Because of both the potential for hiv-1 transmission and the potential for serious adverse reactions in nursing infants, mothers should be instructed not to breastfeed if they are receiving viramune.

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Female gender and higher cd4 cell counts at initiation of therapy place patients at increased risk; women with cd4 cell counts greater than 250 cells mm , including pregnant women receiving viramune in combination with other antiretrovirals for the treatment of hiv-1 infection, are at the greatest risk.

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